采用第II/III代的高精度测序（Automated capture-based next-generation sequencing）技术，美国CAP、CLIA认证检测中心，多学科专业人员分析解读数据（遗传学家、病理学家、肿瘤学临床专家等），为肿瘤患者医生提供详细的靶向用药选择方案以及临床试验选择方案。

肿瘤基因检测

1. Myeloid Molecular Profile 骨髓瘤基因检测 – 40 genes

(ASXL1, BCOR, BRAF, CALR, CEBPA, CBL, CSF3R, DNMT3A, ETV6, EZH2, GATA2, GNAS, IDH1, IDH2, JAK2, KIT, KRAS, MPL, NF1, NPM1, NRAS, PDGFRa, PDGFRb, PHF6, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SMC1A, SMC3, SRSF2, STAG2, STAT3, STAT5b, TET2, TP53, U2AF1, WT1, ZRSR2)

2. MDS Molecular Profile 骨髓增生异常综合征 – 5 genes

(ASXL1, ETV6, EZH2, RUNX1, TP53)

3. MPN Molecular Profile 恶性外周神经瘤 – 5 genes

(CALR, CSF3R, JAK2, MPL, SETBP1)

4. AML Molecular Profile 急性髓系白血病 – 21 genes

(ASXL1, BCOR, CEBPA, DNMT3A, EZH2, IDH1, IDH2, KIT, KRAS, NPM1, NRAS, PHF6, RUNX1, SF3B1, SRSF2, STAG2, TET2, TP53, U2AF1, WT1, ZRSR2)

5. Lymphoid Molecular Profile 淋巴瘤 – 75 genes

(ABL1, ALK, ATM, BCL2, BCL6, BCOR, BIRC3, BRAF, BTK, CARD11, CCND1, CD79A, CD79B, CDKN2A, CREBBP, CTCF, CXCR4, DDX3X, EP300, ETV6, EZH2, FAT1, FBXW7, FOXO1, GNA13, GNAI2, HIST1H1E, ID3, IKZF1, ITPKB, JAK1, JAK2, JAK3, KMT2A/MLL, KRAS, MAPK1, MED12, MEF2B, MYC, MYD88, NF1, NOTCH1, NOTCH2, NRAS, P2RY8, PDGFRb, PIK3CD, PIM1, PLCG2, POT1, PRDM1, PTEN, PTPN11, RB1, RHOA, RIPK1, S1PR2, SAMHD1, SF3B1, SGK1, SPEN, SRC, STAT3, STAT5B, SYK, TBL1XR1, TCF3, TNFAIP3, TNFRSF14, TP53, TRAF2, TRAF3, UBR5, XPO1, ZMYM3)

6. Lung Molecular Profile 肺癌 – 25 genes

(AKT1, ALK, ARAF, BCL2L11, BRAF, DDR2, EGFR, ERBB2, FGFR1, FGFR2, FGFR3, HRAS, IGF1R, KRAS, MAP2K1, MDM2, MET, NRAS, PDGFRá, PIK3CA, PTEN, RET, ROS1, STK11, TP53)

7. Melanoma Molecular Profile 黑色素瘤 – 15 genes

(AKT3, BRAF, CCND1, CDK4, ERBB4, GNA11, GNAQ, KIT, MAP2K1, MAP3K9, MITF, NF1, NRAS, PIK3CA, PTEN)

8. NexCourse? Solid 实体瘤全基因分析 – 110 genes

(ABL1, AKT1, AKT2, AKT3, ALK, APC, AR, ARAF, BAP1, BCL2L11, BRAF, BRCA1, BRCA2, BTK, CBL, CCND1, CCNE1, CDH1, CDK2, CDK4, CDK6, CDKN1B, CDKN2A, CSF1R, CTCF, CTNNB1, DDR2, DDX3X, EGFR, EPHA2, ERBB2, ERBB3, ERBB4, ESR1, ETV6, FBXW7, FGFR1, FGFR2, FGFR3, FGFR4, FLT1 (VEGFR1), FLT3, FOXO1, GATA3, GNA11, GNAQ, GNAS, HIF1A, HNF1A, HRAS, IDH1, IDH2, IGF1R, JAK1, JAK2, JAK3, KDR, KEAP1, KIT, KMT2A/MLL, KRAS, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K9, MAPK1, MCL1, MDM2, MED12, MET, MITF, MTOR, MYC, NF1, NKX2-1, NOTCH1, NOTCH2, NRAS, NTRK1, PALB2, PBRM1, PDGFRa, PDGFRb, PIK3CA, PIK3CD, PIK3R1, PTCH1, PTEN, PTPN11, RB1, RET, RHEB, RHOA, RICTOR, RIT1, ROS1, RUNX1, SMAD4, SMARCB1, SMO, SPEN, SPOP, SRC, STK11, SYK, TP53, TSC1, TSC2, VHL)

9. NexCourse? Complete 实体瘤全基因分析 – 173 genes

(ABL1, AKT1, AKT2, AKT3, ALK, APC, AR, ARAF, ASXL1, ATM, BAP1, BCL2, BCL2L11, BCL6, BCOR, BIRC3, BRAF, BRCA1, BRCA2, BTK, CALR, CARD11, CBL, CCND1, CCNE1, CD79A, CD79B, CDH1, CDK2, CDK4, CDK6, CDKN1B, CDKN2A, CEBPA, CREBBP, CRLF2, CSF1R, CSF3R, CTCF, CTNNB1, CXCR4, DDR2, DDX3X, DNMT3A, EGFR, EP300, EPHA2, ERBB2, ERBB3, ERBB4, ESR1, ETV6, EZH2, FAT1, FBXW7, FGFR1, FGFR2, FGFR3, FGFR4, FLT1 (VEGFR1), FLT3, FOXO1, GATA2, GATA3, GNA11, GNA13, GNAI2, GNAQ, GNAS, HIF1A, HIST1H1E, HNF1A, HRAS, ID3, IDH1, IDH2, IGF1R, IKZF1, ITPKB, JAK1, JAK2, JAK3, KDR, KEAP1, KIT, KMT2A/MLL, KRAS, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K9, MAPK1, MCL1, MDM2, MED12, MEF2B, MET, MITF, MPL, MTOR, MYC, MYD88, NF1, NKX2-1, NOTCH1, NOTCH2, NPM1, NRAS, NTRK1, PALB2, P2RY8, PBRM1, PDGFRA, PDGFRB, PHF6, PIK3CA, PIK3CD, PIK3R1, PIM1, PLCG2, POT1, PRDM1, PTCH1, PTEN, PTPN11, RAD21, RB1, RET, RHEB, RHOA, RICTOR, RIPK1, RIT1, ROS1, RUNX1, S1PR2, SAMHD1, SETBP1, SF3B1, SGK1, SMAD4, SMARCB1, SMC1A, SMC3, SMO, SOX2, SPEN, SPOP, SRC, SRSF2, STAG2, STAT3, STAT5B, STK11, SYK, TBL1XR1, TCF3, TET2, TNFAIP3, TNFRSF14, TP53, TRAF2, TRAF3, TSC1, TSC2, U2AF1, UBR5, VHL, WT1, XPO1, ZMYM3, ZRSR2)

10. MLL-PTD Mutation Analysis

FLT3 Mutation Analysis

病理分子诊断

特殊染色SPECIAL STAINS

 特殊微生物染色 SPECIAL STAINS– MICROORGANISMS

免疫组化IMMUNOHISTOCHEMISTRY

磷酸化免疫组化PHOSPHO IMMUNOHISTOCHEMISTRY

病理报告PATHOLOGYREPORTS

? Compass? and Chart? Blood Evaluation (comprehensive analysis)

? Compass? and Chart? Bone Marrow Evaluation (comprehensive analysis)

? Blood/Bone Marrow Morphology

? Second Opinion Consultation/Central Review

? Hematopathology Consultation

FLOW CYTOMETRY (流式细胞仪检测)

FLOW CYTOMETRY MARKERS 流式细胞仪检测分子

FLOW CYTOMETRY PROFILES

Intelligent Flow Profile

(Markers as needed)

Immunophenotyping（免疫分型）

Kappa, Lambda, 7-AAD, FMC7, HLA-DR, CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11b, CD11c, CD13, CD14, CD16, CD19, CD20, CD22, CD23, CD25, CD33, CD34, CD38, CD45, CD56, CD64, CD103, CD117

Large Granular Lymphocyte (LGL，大颗粒淋巴细胞)

CD3, CD4, CD5, CD8, CD16, CD45, CD56, CD57, Ta/b, Tg/d

Paroxysmal Nocturnal Hemoglobinuria (PNH) Evaluation (阵发性睡眠性血红蛋白)

CD14, CD33, CD45, CD55, CD59, FLAER, 7-AAD

Stem Cell (干细胞)

Ms, 7-AAD, CD34, CD45

Undifferentiated Acute Leukemia (未分化急性白血病)

cCD3, cCD22, CD34, CD41, CD45, CD61, cCD71a, cCD79a, cTdT, cMPO, Glycophorin

Chronic Lymphocytic Leukemia (CLL, 慢性淋巴细胞白血病) Minimal Residual Disease (MRD, 微小残留病) Profile

Kappa, Lambda, FMC-7, 7-AAD, CD3, CD5, CD10, CD19, CD20, CD22, CD23, CD43, CD79b

Mantle Cell Lymphoma (MCL, 套细胞淋巴瘤) Minimal Residual Disease (MRD) Profile

7-AAD, CD3, CD5, CD19, CD20, CD22, CD43, CD79b, CD81

Multiple Myeloma (多发性骨髓瘤) Monitoring/Minimal Residual Disease (MRD) Profile

Kappa, Lambda, CD19, CD20, CD27, CD28, CD38, CD56, CD81, CD138, CD200.

细胞遗传学检测

细胞遗传学报告CYTOGENETICS REPORTS

? Chromosome Analysis and Fluorescence in situ Hybridization (FISH)

? Chromosome Analysis Only

? Fluorescence in situ Hybridization (FISH) Only

FISH MARKERS 
PROBE ABNORMALITY PROBE ABNORMALITY