Grutters博士的治疗小组分析了不同的放射治疗对共计2611名I期非小细胞肺癌(NSCLC)的治疗效果,发现采用X射线的立体定向放射治疗(stereotactic radiotherapy, SBRT)治疗2年总体存活率70%,优于质子刀61%;5年总体存活率42%,优于质子刀40%(见下表)[3]。

不同放射治疗对I期非小细胞肺癌生存率比较
参考资料
Global Burden of Disease Cancer Collaboration.The Global Burden of Cancer 2013. JAMA Oncol. Published online May 28, 2015. doi:10.1001/jamaoncol.2015.0735
Chang JY, Senan S et al. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lungcancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015 May 13. pii: S1470-2045(15)70168-3. doi: 10.1016/S1470-2045(15)70168-3.
Grutters JP, Kessels AG, Pijls-Johannesma M, De Ruysscher D, Joore MA, Lambin P.Comparison of the effectiveness of radiotherapy with photons, protons and carbon-ions for non-small cell lung cancer: a meta-analysis. Radiotherapy and Oncology 2010; 95(1): 32-40.